Monkeypox 2022 global epidemiology; Report 2022-09-19

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 115 countries (either confirmed or suspected cases), with 109 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 61648 confirmed and 3673 suspected cases (as of 2022-09-19; Figure 1A). Since 2022-09-15, 977 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 22958 5
Spain 7037 2
Brazil 6649 10
France 3889 2
Germany 3556 0
England 3383 1
Peru 2054 6
Canada 1362 3
Colombia 1260 34
Netherlands 1209 1
Mexico 1051 33
Portugal 908 4
Italy 828 2
Belgium 744 2
Chile 684 40
Switzerland 498 2
Austria 298 4
Nigeria 277 25
Israel 246 0
Argentina 221 0
Democratic Republic Of The Congo 195 0
Denmark 183 1
Sweden 179 6
Ireland 173 8
Puerto Rico 163 18
Poland 160 10
Bolivia 134 12
Australia 132 2
Scotland 92 3
Norway 89 7
Ghana 84 10
Hungary 75 5
Greece 69 4
Ecuador 68 15
Czech Republic 62 6
Luxembourg 55 1
Slovenia 46 2
Wales 46 2
Romania 37 2
Malta 33 0
Finland 33 10
Serbia 31 0
Northern Ireland 31 3
Dominican Republic 30 233
Croatia 27 0
Singapore 19 18
United Arab Emirates 16 0
Slovakia 14 0
Guatemala 12 0
Iceland 12 0
India 12 9
Jamaica 12 33
Panama 12 0
Lebanon 11 37
Turkey 11 0
Estonia 11 10
Saudi Arabia 8 0
Central African Republic 8 0
Cameroon 7 0
Martinique 7 0
Thailand 7 0
Bulgaria 6 20
Gibraltar 6 0
Cyprus 5 0
Uruguay 5 0
South Africa 5 0
New Zealand 5 0
Lithuania 5 0
Costa Rica 4 33
Sudan 4 100
Honduras 4 0
Qatar 4 33
Japan 4 0
Latvia 4 0
Philippines 4 0
Andorra 4 0
Bosnia And Herzegovina 3 0
Republic of Congo 3 0
Benin 3 0
Morocco 3 0
Aruba 3 50
Taiwan 3 -25
Monaco 3 0
Venezuela 3 0
El Salvador 2 100
Russia 2 0
Moldova 2 0
Bahamas 2 0
Greenland 2 0
Guyana 2 0
Liberia 2 0
Cuba 2 0
South Korea 2 -33
South Sudan 2 0
Georgia 2 0
Montenegro 2 0
Guadeloupe 1 0
Paraguay 1 0
Bermuda 1 0
Barbados 1 0
Curaçao 1 0
Hong Kong 1 0
Indonesia 1 0
Iran 1 0
New Caledonia 1 0
Egypt 1 0
Saint Martin (French part) 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 61648 number of confirmed cases, 244 reported travel history. For 137 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.41 days (median 2 days) and varied by country (n = 1059 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 769, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is United Kingdom. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext