Monkeypox 2022 global epidemiology; Report 2022-09-14

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 114 countries (either confirmed or suspected cases), with 108 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 58956 confirmed and 3382 suspected cases (as of 2022-09-14; Figure 1A). Since 2022-09-12, 761 new confirmed cases have been reported, and 1 new country has been added to the list (Jordan) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 21835 5
Spain 6947 2
Brazil 6129 10
France 3776 3
Germany 3547 1
England 3383 1
Peru 1964 13
Canada 1320 0
Colombia 1260 34
Netherlands 1195 1
Portugal 898 3
Italy 813 3
Mexico 788 0
Belgium 726 0
Switzerland 490 1
Chile 486 8
Austria 286 2
Israel 246 0
Argentina 221 30
Nigeria 220 0
Democratic Republic Of The Congo 196 0
Denmark 183 2
Sweden 174 5
Ireland 160 0
Poland 156 7
Puerto Rico 152 13
Australia 129 3
Bolivia 119 29
Scotland 92 3
Norway 85 2
Ghana 76 0
Hungary 71 0
Greece 66 6
Czech Republic 62 6
Ecuador 59 0
Luxembourg 54 1
Slovenia 46 2
Wales 46 2
Romania 37 2
Finland 33 10
Malta 33 0
Northern Ireland 31 3
Serbia 31 0
Croatia 27 0
Singapore 16 0
United Arab Emirates 16 0
Slovakia 14 0
Panama 12 0
Jamaica 12 71
Iceland 12 0
Guatemala 12 9
India 11 0
Turkey 11 0
Lebanon 11 83
Estonia 10 0
Dominican Republic 9 0
Saudi Arabia 8 0
Central African Republic 8 0
Cameroon 7 0
Thailand 7 0
Martinique 7 16
Gibraltar 6 0
Cyprus 5 0
South Africa 5 0
Bulgaria 5 0
Lithuania 5 0
Uruguay 5 0
New Zealand 5 0
Taiwan 4 0
Philippines 4 0
Andorra 4 0
Honduras 4 0
Japan 4 0
Latvia 4 0
Republic of Congo 3 0
Monaco 3 0
Costa Rica 3 0
South Korea 3 0
Sudan 3 50
Benin 3 0
Qatar 3 0
Bosnia And Herzegovina 3 0
Morocco 3 0
Venezuela 3 0
Liberia 2 0
South Sudan 2 0
Bahamas 2 0
Aruba 2 0
Greenland 2 0
Moldova 2 0
Guyana 2 0
Georgia 2 0
Montenegro 2 0
Russia 2 100
Cuba 2 0
Saint Martin (French part) 1 0
Bermuda 1 0
Barbados 1 0
Curaçao 1 0
Indonesia 1 0
Guadeloupe 1 0
El Salvador 1 0
Paraguay 1 0
Hong Kong 1 0
New Caledonia 1 0
Iran 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 58956 number of confirmed cases, 242 reported travel history. For 135 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.4 days (median 2 days) and varied by country (n = 1052 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 839, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext