Monkeypox 2022 global epidemiology; Report 2022-09-13

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 113 countries (either confirmed or suspected cases), with 107 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 58195 confirmed and 3382 suspected cases (as of 2022-09-13; Figure 1A). Since 2022-09-09, 901 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 21761 9
Spain 6884 2
Brazil 6033 11
France 3776 3
Germany 3530 0
England 3320 0
Peru 1937 12
Canada 1320 2
Netherlands 1195 2
Colombia 938 61
Portugal 871 0
Italy 805 2
Mexico 788 56
Belgium 726 0
Chile 486 8
Switzerland 485 1
Austria 286 4
Israel 245 1
Argentina 221 30
Nigeria 220 0
Democratic Republic Of The Congo 196 0
Denmark 181 1
Sweden 168 3
Ireland 160 11
Poland 145 2
Puerto Rico 137 20
Australia 129 3
Bolivia 119 29
Scotland 89 0
Norway 83 0
Ghana 76 35
Hungary 71 1
Greece 66 13
Ecuador 59 11
Czech Republic 58 20
Luxembourg 54 1
Slovenia 45 2
Wales 45 0
Romania 36 0
Malta 33 6
Serbia 31 0
Finland 30 36
Northern Ireland 30 0
Croatia 27 3
United Arab Emirates 16 0
Singapore 16 0
Slovakia 14 0
Iceland 12 0
Guatemala 12 20
Panama 12 0
India 11 10
Turkey 11 0
Estonia 10 0
Dominican Republic 9 0
Jamaica 9 80
Lebanon 8 33
Saudi Arabia 8 0
Central African Republic 8 0
Cameroon 7 0
Martinique 7 16
Thailand 7 0
Gibraltar 6 0
Cyprus 5 0
Uruguay 5 25
South Africa 5 0
Bulgaria 5 25
New Zealand 5 25
Lithuania 5 0
Philippines 4 0
Honduras 4 0
Taiwan 4 33
Japan 4 0
Latvia 4 0
Andorra 4 0
Benin 3 0
South Korea 3 50
Morocco 3 0
Venezuela 3 0
Qatar 3 0
Republic of Congo 3 0
Monaco 3 0
Costa Rica 3 0
Bosnia And Herzegovina 3 0
Russia 2 100
Guyana 2 0
Montenegro 2 0
Georgia 2 0
Aruba 2 0
Bahamas 2 0
Moldova 2 0
Cuba 2 0
Greenland 2 0
Liberia 2 0
Sudan 2 0
Guadeloupe 1 0
Paraguay 1 0
Barbados 1 0
Curaçao 1 0
Bermuda 1 0
Indonesia 1 0
Iran 1 0
Saint Martin (French part) 1 0
El Salvador 1 0
New Caledonia 1 0
Hong Kong 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 58195 number of confirmed cases, 241 reported travel history. For 135 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.4 days (median 2 days) and varied by country (n = 1052 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 839, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext