Monkeypox 2022 global epidemiology; Report 2022-09-06

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 110 countries (either confirmed or suspected cases), with 104 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 53446 confirmed and 3163 suspected cases (as of 2022-09-06; Figure 1A). Since 2022-09-02, 497 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 19852 10
Spain 6645 2
Brazil 5197 10
France 3638 2
Germany 3493 1
England 3257 0
Peru 1546 5
Canada 1286 4
Netherlands 1166 2
Portugal 871 2
Italy 773 4
Belgium 706 5
Colombia 582 0
Mexico 504 30
Switzerland 476 4
Chile 381 10
Austria 273 3
Israel 239 2
Nigeria 220 27
Democratic Republic Of The Congo 195 19
Denmark 177 1
Argentina 170 27
Sweden 161 3
Ireland 144 0
Poland 130 1
Australia 124 16
Puerto Rico 114 6
Bolivia 86 24
Scotland 85 0
Norway 82 2
Hungary 70 4
Greece 58 3
Ghana 56 0
Luxembourg 53 0
Ecuador 53 6
Czech Republic 48 4
Wales 44 0
Slovenia 43 0
Romania 36 0
Malta 31 0
Serbia 31 0
Northern Ireland 27 0
Croatia 26 0
Finland 22 0
Singapore 16 0
United Arab Emirates 16 0
Iceland 12 0
Slovakia 12 0
Turkey 11 0
India 10 0
Guatemala 10 66
Panama 10 11
Estonia 10 0
Dominican Republic 9 0
Central African Republic 8 0
Saudi Arabia 8 14
Cameroon 7 0
Thailand 7 0
Lebanon 6 0
Martinique 6 0
Gibraltar 6 0
South Africa 5 0
Jamaica 5 25
Cyprus 5 0
Lithuania 5 0
Andorra 4 0
Latvia 4 0
Bulgaria 4 0
Honduras 4 33
Japan 4 0
Philippines 4 0
Uruguay 4 33
New Zealand 4 0
Benin 3 0
Taiwan 3 0
Venezuela 3 0
Qatar 3 0
Republic of Congo 3 0
Bosnia And Herzegovina 3 0
Monaco 3 0
Morocco 3 0
Costa Rica 3 0
Aruba 2 0
Bahamas 2 0
Sudan 2 0
Cuba 2 100
Montenegro 2 0
Georgia 2 0
Greenland 2 0
Guyana 2 0
Liberia 2 0
Moldova 2 0
Curaçao 1 0
South Korea 1 0
Saint Martin (French part) 1 0
Russia 1 0
Bermuda 1 0
Indonesia 1 0
Iran 1 0
Barbados 1 0
Paraguay 1 0
New Caledonia 1 0
Guadeloupe 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 53446 number of confirmed cases, 238 reported travel history. For 133 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.56 days (median 3 days) and varied by country (n = 1010 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 784, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext