Monkeypox 2022 global epidemiology; Report 2022-08-31

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 109 countries (either confirmed or suspected cases), with 103 confirming transmission, 6 countries continuing to have suspected cases only, and 32 countries having discarded cases that were suspected, out of which 10 have only discarded cases. Overall there are 50118 confirmed and 2589 suspected cases (as of 2022-08-31; Figure 1A). Since 2022-08-29, 1584 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 17995 13
Spain 6459 2
Brazil 4693 17
France 3539 23
Germany 3455 3
England 3257 2
Peru 1463 21
Canada 1228 1
Netherlands 1136 4
Portugal 846 4
Italy 740 3
Belgium 671 0
Colombia 582 113
Switzerland 456 9
Mexico 386 0
Chile 344 27
Austria 265 14
Israel 234 9
Denmark 174 2
Nigeria 172 0
Democratic Republic Of The Congo 163 0
Sweden 156 4
Ireland 144 12
Argentina 133 84
Poland 128 5
Puerto Rico 107 38
Australia 106 17
Scotland 85 8
Norway 80 5
Bolivia 69 40
Hungary 67 4
Ghana 56 19
Greece 56 7
Luxembourg 53 12
Ecuador 50 42
Czech Republic 46 12
Wales 44 0
Slovenia 43 0
Romania 36 2
Malta 31 0
Serbia 31 0
Northern Ireland 27 0
Croatia 26 18
Finland 22 0
United Arab Emirates 16 0
Singapore 16 6
Slovakia 12 0
Iceland 12 0
Turkey 11 0
Estonia 10 0
India 10 0
Panama 9 28
Dominican Republic 9 28
Central African Republic 8 0
Thailand 7 40
Cameroon 7 0
Saudi Arabia 7 16
Martinique 6 200
Guatemala 6 50
Gibraltar 6 0
Lebanon 6 0
South Africa 5 0
Cyprus 5 25
Lithuania 5 0
Philippines 4 0
New Zealand 4 0
Andorra 4 0
Jamaica 4 0
Bulgaria 4 0
Latvia 4 0
Japan 4 0
Qatar 3 0
Bosnia And Herzegovina 3 0
Taiwan 3 0
Honduras 3 0
Republic of Congo 3 0
Benin 3 0
Costa Rica 3 0
Uruguay 3 0
Monaco 3 0
Venezuela 3 200
Morocco 3 200
Bahamas 2 0
Aruba 2 100
Sudan 2 0
Greenland 2 0
Georgia 2 0
Guyana 2 100
Liberia 2 0
Moldova 2 0
Montenegro 2 0
Curaçao 1 0
Cuba 1 0
South Korea 1 0
Guadeloupe 1 0
Saint Martin (French part) 1 0
Bermuda 1 0
Russia 1 0
Indonesia 1 0
Barbados 1 0
Iran 1 0
New Caledonia 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 50118 number of confirmed cases, 237 reported travel history. For 132 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.56 days (median 3 days) and varied by country (n = 1005 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 776, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext