Monkeypox 2022 global epidemiology; Report 2022-08-29

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 109 countries (either confirmed or suspected cases), with 103 confirming transmission, 6 countries continuing to have suspected cases only, and 32 countries having discarded cases that were suspected, out of which 10 have only discarded cases. Overall there are 47491 confirmed and 2589 suspected cases (as of 2022-08-29; Figure 1A). Since 2022-08-25, 1324 new confirmed cases have been reported, and 1 new country has been added to the list (Paraguay) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 16837 19
Spain 6459 11
Brazil 4216 11
France 3398 18
Germany 3387 3
England 3191 4
Peru 1300 15
Canada 1228 5
Netherlands 1136 4
Portugal 846 9
Italy 740 7
Belgium 671 7
Switzerland 436 9
Mexico 386 53
Colombia 273 66
Chile 270 30
Austria 253 16
Israel 215 3
Nigeria 172 0
Denmark 171 1
Democratic Republic Of The Congo 163 0
Sweden 154 10
Argentina 133 84
Ireland 128 13
Poland 122 17
Australia 103 14
Puerto Rico 90 36
Norway 79 3
Scotland 78 4
Hungary 64 3
Greece 54 8
Bolivia 53 23
Luxembourg 50 11
Ghana 47 0
Wales 44 2
Slovenia 43 0
Czech Republic 41 13
Romania 35 6
Ecuador 35 75
Serbia 31 0
Malta 31 0
Northern Ireland 27 0
Croatia 25 47
Finland 22 0
Singapore 16 6
United Arab Emirates 16 0
Slovakia 12 20
Iceland 12 0
Turkey 11 120
Estonia 10 11
India 10 0
Dominican Republic 9 50
Central African Republic 8 0
Panama 8 14
Saudi Arabia 7 16
Cameroon 7 0
Guatemala 6 100
Gibraltar 6 0
Lebanon 6 0
Lithuania 5 0
South Africa 5 0
Thailand 5 0
Philippines 4 33
Andorra 4 0
New Zealand 4 0
Japan 4 0
Bulgaria 4 0
Cyprus 4 0
Jamaica 4 0
Latvia 4 0
Honduras 3 0
Qatar 3 0
Republic of Congo 3 0
Venezuela 3 200
Uruguay 3 50
Benin 3 0
Monaco 3 0
Bosnia And Herzegovina 3 0
Taiwan 3 0
Morocco 3 200
Costa Rica 3 0
Montenegro 2 100
Sudan 2 0
Martinique 2 0
Liberia 2 0
Greenland 2 0
Moldova 2 0
Georgia 2 0
South Korea 1 0
Guadeloupe 1 0
New Caledonia 1 0
Indonesia 1 0
Iran 1 0
Bermuda 1 0
Saint Martin (French part) 1 0
Barbados 1 0
Russia 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 47491 number of confirmed cases, 236 reported travel history. For 133 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.56 days (median 3 days) and varied by country (n = 1005 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 673, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext