Monkeypox 2022 global epidemiology; Report 2022-08-26

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 109 countries (either confirmed or suspected cases), with 102 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 10 have only discarded cases. Overall there are 46167 confirmed and 2603 suspected cases (as of 2022-08-26; Figure 1A). Since 2022-08-24, 1039 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 16514 17
Spain 6284 8
Brazil 4144 20
Germany 3387 3
England 3191 4
France 2873 0
Peru 1257 34
Canada 1206 7
Netherlands 1136 4
Portugal 810 5
Italy 714 3
Belgium 671 7
Switzerland 431 8
Mexico 386 53
Colombia 273 111
Chile 270 42
Austria 234 7
Israel 215 10
Nigeria 172 0
Denmark 169 3
Democratic Republic Of The Congo 163 0
Sweden 154 10
Ireland 128 13
Poland 121 16
Australia 103 14
Puerto Rico 90 36
Scotland 78 4
Norway 77 1
Argentina 72 0
Hungary 64 3
Greece 54 8
Bolivia 49 32
Luxembourg 47 4
Ghana 47 0
Wales 44 2
Slovenia 43 0
Czech Republic 41 13
Romania 35 6
Ecuador 35 75
Serbia 31 0
Malta 31 0
Northern Ireland 27 0
Croatia 25 47
Finland 22 0
United Arab Emirates 16 0
Singapore 16 6
Slovakia 12 20
Iceland 12 0
Turkey 11 120
Estonia 10 11
India 10 0
Dominican Republic 9 50
Central African Republic 8 0
Panama 8 60
Cameroon 7 0
Saudi Arabia 7 16
Lebanon 6 0
Gibraltar 6 0
Thailand 5 0
South Africa 5 0
Lithuania 5 0
Guatemala 4 33
Philippines 4 33
Bulgaria 4 0
Cyprus 4 0
Jamaica 4 0
Japan 4 0
Andorra 4 0
Latvia 4 0
New Zealand 4 0
Taiwan 3 0
Republic of Congo 3 0
Honduras 3 0
Venezuela 3 200
Uruguay 3 50
Bosnia And Herzegovina 3 0
Benin 3 0
Monaco 3 0
Costa Rica 3 0
Qatar 3 0
Liberia 2 0
Sudan 2 0
Montenegro 2 100
Moldova 2 0
Georgia 2 0
Greenland 2 0
Martinique 2 0
Bermuda 1 0
Barbados 1 0
Iran 1 0
New Caledonia 1 0
Guadeloupe 1 0
Morocco 1 0
Saint Martin (French part) 1 0
Russia 1 0
South Korea 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 46167 number of confirmed cases, 235 reported travel history. For 132 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.56 days (median 3 days) and varied by country (n = 1005 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 821, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext