Monkeypox 2022 global epidemiology; Report 2022-08-23

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 104 countries (either confirmed or suspected cases), with 97 confirming transmission, 7 countries continuing to have suspected cases only, and 31 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 41743 confirmed and 2605 suspected cases (as of 2022-08-23; Figure 1A). Since 2022-08-19, 654 new confirmed cases have been reported, and 1 new country has been added to the list (Indonesia) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 14050 18
Spain 5792 0
Brazil 3788 26
Germany 3266 2
England 3050 0
France 2873 8
Canada 1168 8
Peru 1128 35
Netherlands 1087 6
Portugal 770 0
Italy 689 4
Belgium 624 0
Switzerland 399 0
Mexico 252 71
Austria 217 9
Israel 208 10
Chile 207 46
Nigeria 172 9
Denmark 169 9
Colombia 164 27
Democratic Republic Of The Congo 163 0
Sweden 139 7
Ireland 113 11
Poland 104 9
Australia 90 26
Norway 76 2
Scotland 75 0
Argentina 72 46
Puerto Rico 66 32
Hungary 62 21
Greece 50 4
Ghana 47 0
Luxembourg 45 9
Wales 43 0
Bolivia 43 186
Slovenia 43 0
Czech Republic 36 2
Romania 33 6
Serbia 31 34
Malta 31 3
Northern Ireland 27 0
Finland 22 0
Ecuador 20 25
Croatia 17 41
United Arab Emirates 16 0
Singapore 15 0
Iceland 12 9
Slovakia 10 0
India 10 0
Estonia 9 0
Central African Republic 8 0
Panama 7 133
Cameroon 7 0
Saudi Arabia 6 20
Lebanon 6 0
Dominican Republic 6 20
Gibraltar 6 0
South Africa 5 25
Turkey 5 0
Thailand 5 0
Lithuania 5 0
Japan 4 0
Bulgaria 4 0
Cyprus 4 33
Jamaica 4 0
Andorra 4 0
Latvia 4 33
New Zealand 4 0
Taiwan 3 0
Bosnia And Herzegovina 3 200
Honduras 3 0
Guatemala 3 0
Qatar 3 0
Republic of Congo 3 0
Monaco 3 0
Benin 3 0
Costa Rica 3 0
Philippines 3 200
Sudan 2 100
Uruguay 2 0
Moldova 2 100
Georgia 2 100
Greenland 2 0
Liberia 2 0
Martinique 2 0
South Korea 1 0
Russia 1 0
Guadeloupe 1 0
Iran 1 0
Bermuda 1 0
New Caledonia 1 0
Morocco 1 0
Barbados 1 0
Montenegro 1 0
Venezuela 1 0
Saint Martin (French part) 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 41743 number of confirmed cases, 228 reported travel history. For 128 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.54 days (median 3 days) and varied by country (n = 998 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 783, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext