Monkeypox 2022 global epidemiology; Report 2022-08-22

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 103 countries (either confirmed or suspected cases), with 96 confirming transmission, 7 countries continuing to have suspected cases only, and 31 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 41089 confirmed and 2605 suspected cases (as of 2022-08-22; Figure 1A). Since 2022-08-18, 1321 new confirmed cases have been reported (Figure 1B).

Turn over for figure →

Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 14050 26
Spain 5792 1
Brazil 3450 19
Germany 3266 3
England 3050 5
France 2873 8
Canada 1125 6
Netherlands 1087 6
Peru 937 20
Portugal 770 0
Italy 689 6
Belgium 624 14
Switzerland 399 3
Mexico 252 71
Austria 217 9
Israel 194 2
Chile 189 34
Nigeria 172 9
Democratic Republic Of The Congo 163 0
Denmark 163 7
Sweden 139 10
Colombia 129 0
Ireland 113 11
Poland 104 22
Australia 90 26
Norway 76 2
Scotland 75 8
Argentina 72 46
Puerto Rico 66 32
Hungary 62 21
Greece 50 4
Ghana 47 0
Luxembourg 45 9
Wales 43 7
Slovenia 43 0
Bolivia 37 146
Czech Republic 36 2
Romania 33 6
Serbia 31 34
Malta 31 3
Northern Ireland 27 8
Finland 22 0
Ecuador 20 25
Croatia 17 41
United Arab Emirates 16 0
Singapore 15 0
Iceland 12 9
Slovakia 10 0
India 10 0
Estonia 9 0
Central African Republic 8 0
Cameroon 7 0
Saudi Arabia 6 20
Lebanon 6 0
Dominican Republic 6 20
Gibraltar 6 0
Panama 5 150
South Africa 5 25
Turkey 5 0
Thailand 5 25
Lithuania 5 0
Andorra 4 0
Bulgaria 4 0
Japan 4 0
Jamaica 4 0
Latvia 4 33
New Zealand 4 0
Cyprus 4 33
Philippines 3 200
Costa Rica 3 0
Honduras 3 0
Guatemala 3 0
Qatar 3 0
Republic of Congo 3 0
Bosnia And Herzegovina 3 200
Monaco 3 0
Taiwan 3 0
Benin 3 0
Sudan 2 100
Uruguay 2 0
Moldova 2 100
Georgia 2 100
Greenland 2 0
Liberia 2 0
Martinique 2 0
South Korea 1 0
Russia 1 0
Guadeloupe 1 0
Bermuda 1 0
New Caledonia 1 0
Morocco 1 0
Barbados 1 0
Montenegro 1 0
Venezuela 1 0
Saint Martin (French part) 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 41089 number of confirmed cases, 227 reported travel history. For 127 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.54 days (median 3 days) and varied by country (n = 998 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 525, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext