Monkeypox 2022 global epidemiology; Report 2022-08-19

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 103 countries (either confirmed or suspected cases), with 96 confirming transmission, 7 countries continuing to have suspected cases only, and 31 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 39768 confirmed and 2446 suspected cases (as of 2022-08-19; Figure 1A). Since 2022-08-17, 1033 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 13452 25
Spain 5792 1
Germany 3213 3
Brazil 3184 29
England 3050 5
France 2735 2
Canada 1076 1
Netherlands 1025 0
Peru 891 36
Portugal 770 0
Italy 662 2
Belgium 624 14
Switzerland 399 6
Mexico 252 71
Austria 216 9
Israel 194 11
Chile 189 50
Democratic Republic Of The Congo 163 0
Nigeria 157 0
Denmark 155 9
Colombia 129 134
Sweden 129 2
Ireland 113 11
Poland 104 22
Australia 83 16
Scotland 75 8
Norway 74 5
Argentina 72 46
Puerto Rico 66 46
Hungary 62 21
Greece 49 2
Ghana 47 0
Luxembourg 43 4
Wales 43 7
Slovenia 43 0
Czech Republic 35 20
Romania 32 3
Malta 30 0
Northern Ireland 27 8
Bolivia 27 145
Serbia 23 0
Finland 22 0
Ecuador 20 25
United Arab Emirates 16 0
Singapore 15 0
Croatia 12 0
Iceland 11 0
Slovakia 10 0
India 10 11
Estonia 9 0
Central African Republic 8 0
Cameroon 7 0
Lebanon 6 0
Dominican Republic 6 20
Gibraltar 6 0
Saudi Arabia 5 0
Turkey 5 0
Thailand 5 25
Lithuania 5 0
Japan 4 0
Bulgaria 4 0
South Africa 4 33
Jamaica 4 0
Andorra 4 0
New Zealand 4 0
Panama 4 100
Latvia 4 33
Costa Rica 3 0
Bosnia And Herzegovina 3 200
Taiwan 3 0
Cyprus 3 0
Benin 3 0
Republic of Congo 3 0
Qatar 3 0
Guatemala 3 0
Uruguay 2 0
Greenland 2 0
Liberia 2 0
Martinique 2 0
Barbados 1 0
Morocco 1 0
Venezuela 1 0
Bermuda 1 0
Philippines 1 0
Sudan 1 0
New Caledonia 1 0
South Korea 1 0
Georgia 1 0
Montenegro 1 0
Saint Martin (French part) 1 0
Russia 1 0
Guadeloupe 1 0
Moldova 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 39768 number of confirmed cases, 223 reported travel history. For 125 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.54 days (median 3 days) and varied by country (n = 998 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 525, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext