Monkeypox 2022 global epidemiology; Report 2022-08-15

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 101 countries (either confirmed or suspected cases), with 93 confirming transmission, 7 countries continuing to have suspected cases only, and 31 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 35058 confirmed and 2446 suspected cases (as of 2022-08-15; Figure 1A). Since 2022-08-11, 1401 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 10726 43
Spain 5719 15
Germany 3102 6
England 2883 5
France 2659 9
Brazil 2458 22
Canada 1058 10
Netherlands 1025 6
Portugal 770 8
Peru 653 29
Italy 644 18
Belgium 546 13
Switzerland 376 12
Austria 198 23
Israel 174 4
Democratic Republic Of The Congo 163 0
Nigeria 157 18
Mexico 147 61
Denmark 141 14
Chile 126 38
Sweden 126 13
Ireland 101 4
Poland 85 11
Australia 71 22
Norway 70 6
Scotland 69 2
Colombia 55 0
Hungary 51 21
Argentina 49 53
Greece 48 23
Ghana 47 34
Puerto Rico 45 32
Slovenia 43 13
Luxembourg 41 32
Wales 40 8
Romania 31 40
Malta 30 76
Czech Republic 29 3
Northern Ireland 25 0
Serbia 23 130
Finland 22 0
United Arab Emirates 16 0
Ecuador 16 128
Singapore 15 0
Croatia 12 0
Iceland 11 0
Bolivia 11 120
Slovakia 10 25
India 9 0
Estonia 9 0
Central African Republic 8 0
Cameroon 7 0
Lebanon 6 0
Gibraltar 6 20
Turkey 5 0
Lithuania 5 66
Dominican Republic 5 25
Saudi Arabia 5 0
Japan 4 100
Thailand 4 0
Bulgaria 4 0
Jamaica 4 33
Andorra 4 0
New Zealand 4 33
South Africa 3 0
Cyprus 3 0
Latvia 3 0
Costa Rica 3 0
Benin 3 0
Republic of Congo 3 50
Qatar 3 50
Guatemala 3 50
Taiwan 3 50
Uruguay 2 0
Panama 2 100
Liberia 2 100
Martinique 2 100
Barbados 1 0
Bermuda 1 0
New Caledonia 1 0
Venezuela 1 0
Philippines 1 0
Bosnia And Herzegovina 1 0
Sudan 1 0
South Korea 1 0
Georgia 1 0
Montenegro 1 0
Saint Martin (French part) 1 0
Russia 1 0
Guadeloupe 1 0
Morocco 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 35058 number of confirmed cases, 220 reported travel history. For 123 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.57 days (median 3 days) and varied by country (n = 989 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 403, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext