Monkeypox 2022 global epidemiology; Report 2022-08-12

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 101 countries (either confirmed or suspected cases), with 93 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 33657 confirmed and 2416 suspected cases (as of 2022-08-12; Figure 1A). Since 2022-08-10, 1258 new confirmed cases have been reported, and 2 new countries have been added to the list (Greenland, Moldova) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 10361 46
Spain 5162 4
Germany 3063 6
England 2883 13
France 2588 15
Brazil 2415 40
Netherlands 1025 7
Canada 1011 13
Portugal 710 0
Peru 632 85
Italy 599 9
Belgium 546 13
Switzerland 368 16
Austria 175 9
Israel 174 8
Democratic Republic Of The Congo 163 0
Mexico 147 61
Denmark 135 25
Nigeria 133 0
Sweden 126 13
Ireland 101 4
Chile 91 33
Poland 85 34
Scotland 69 6
Norway 67 3
Australia 67 24
Colombia 55 111
Hungary 51 21
Ghana 47 34
Slovenia 43 13
Greece 41 24
Wales 40 25
Argentina 37 15
Puerto Rico 34 61
Luxembourg 34 13
Malta 30 76
Czech Republic 29 16
Romania 28 27
Northern Ireland 25 4
Serbia 23 130
Finland 22 10
Ecuador 16 128
United Arab Emirates 16 0
Singapore 15 0
Croatia 12 0
Iceland 11 10
Bolivia 10 233
India 9 12
Estonia 9 12
Central African Republic 8 0
Slovakia 8 33
Cameroon 7 0
Lebanon 6 50
Gibraltar 5 0
Turkey 5 400
Saudi Arabia 5 25
Japan 4 100
Thailand 4 0
Bulgaria 4 0
Dominican Republic 4 0
Jamaica 4 100
Andorra 4 33
New Zealand 4 33
South Africa 3 0
Lithuania 3 200
Taiwan 3 50
Latvia 3 0
Costa Rica 3 0
Cyprus 3 200
Benin 3 0
Qatar 3 50
Guatemala 3 200
Uruguay 2 0
Republic of Congo 2 0
Panama 2 100
Barbados 1 0
Bosnia And Herzegovina 1 0
New Caledonia 1 0
Venezuela 1 0
Bermuda 1 0
Philippines 1 0
Sudan 1 0
Martinique 1 0
South Korea 1 0
Georgia 1 0
Montenegro 1 0
Liberia 1 0
Russia 1 0
Guadeloupe 1 0
Morocco 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 33657 number of confirmed cases, 220 reported travel history. For 123 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.96 days (median 2 days) and varied by country (n = 957 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 345, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext