Monkeypox 2022 global epidemiology; Report 2022-08-11

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 100 countries (either confirmed or suspected cases), with 92 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 32399 confirmed and 2416 suspected cases (as of 2022-08-11; Figure 1A). Since 2022-08-09, 959 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 9461 43
Spain 5162 12
Germany 3025 6
England 2883 13
France 2588 15
Brazil 2293 55
Canada 989 10
Netherlands 959 0
Portugal 710 12
Italy 599 18
Peru 583 71
Belgium 546 13
Switzerland 347 11
Austria 175 29
Israel 174 8
Democratic Republic Of The Congo 163 52
Mexico 147 61
Nigeria 133 0
Denmark 129 19
Sweden 123 10
Ireland 101 4
Chile 91 33
Poland 85 34
Scotland 69 6
Australia 67 24
Norway 66 4
Colombia 55 175
Hungary 51 21
Slovenia 41 10
Greece 41 24
Wales 40 25
Argentina 37 15
Ghana 35 0
Puerto Rico 34 61
Luxembourg 34 13
Malta 30 76
Czech Republic 29 16
Romania 28 27
Northern Ireland 25 4
Serbia 23 130
Finland 22 10
United Arab Emirates 16 0
Singapore 15 15
Croatia 12 0
Iceland 11 10
Ecuador 10 66
India 9 12
Estonia 9 12
Central African Republic 8 0
Slovakia 8 33
Cameroon 7 16
Lebanon 6 50
Saudi Arabia 5 25
Bolivia 5 400
Turkey 5 400
Gibraltar 5 0
Thailand 4 100
Andorra 4 33
Dominican Republic 4 33
Bulgaria 4 0
Japan 3 50
Benin 3 0
China 3 50
Costa Rica 3 0
South Africa 3 0
Cyprus 3 200
Jamaica 3 50
New Zealand 3 0
Latvia 3 0
Lithuania 3 200
Qatar 3 50
Uruguay 2 0
Panama 2 100
Taiwan 2 0
Republic of Congo 2 0
Guatemala 2 100
New Caledonia 1 0
Martinique 1 0
South Korea 1 0
Montenegro 1 0
Russia 1 0
Philippines 1 0
Morocco 1 0
Georgia 1 0
Bosnia And Herzegovina 1 0
Bermuda 1 0
Guadeloupe 1 0
Barbados 1 0
Venezuela 1 0
Sudan 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 32399 number of confirmed cases, 218 reported travel history. For 122 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.96 days (median 2 days) and varied by country (n = 957 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 345, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 4% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext