Monkeypox 2022 global epidemiology; Report 2022-08-09

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 100 countries (either confirmed or suspected cases), with 92 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 29068 confirmed and 2419 suspected cases (as of 2022-08-09; Figure 1A). Since 2022-08-05, 1480 new confirmed cases have been reported, and 1 new country has been added to the list (Saint Martin (French part)) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 7492 29
Spain 4942 7
Germany 2916 7
England 2730 7
France 2423 23
Brazil 2004 35
Netherlands 959 3
Canada 957 19
Portugal 710 12
Italy 545 7
Peru 505 61
Belgium 482 0
Switzerland 335 12
Israel 166 8
Democratic Republic Of The Congo 163 52
Austria 160 21
Nigeria 133 0
Denmark 123 24
Sweden 111 30
Ireland 97 14
Mexico 91 42
Chile 91 65
Poland 76 28
Scotland 67 3
Norway 66 15
Australia 58 28
Colombia 55 243
Hungary 42 7
Greece 39 21
Slovenia 38 8
Wales 37 15
Ghana 35 0
Puerto Rico 34 61
Argentina 32 39
Luxembourg 31 10
Czech Republic 28 40
Northern Ireland 25 4
Finland 22 29
Romania 22 4
Malta 17 0
United Arab Emirates 16 0
Singapore 15 25
Croatia 12 0
Iceland 11 10
Serbia 10 0
India 9 12
Estonia 9 12
Slovakia 8 33
Central African Republic 8 0
Ecuador 7 40
Cameroon 7 16
Lebanon 6 50
Saudi Arabia 5 25
Bolivia 5 400
Turkey 5 400
Gibraltar 5 0
Thailand 4 100
Andorra 4 33
Bulgaria 4 0
Dominican Republic 4 33
Cyprus 3 200
Jamaica 3 50
Benin 3 0
Costa Rica 3 0
South Africa 3 0
New Zealand 3 0
Latvia 3 0
Taiwan 2 0
Uruguay 2 100
Republic of Congo 2 0
Qatar 2 0
Japan 2 0
China 2 0
Russia 1 0
Venezuela 1 0
Barbados 1 0
Philippines 1 0
Bermuda 1 0
Bosnia And Herzegovina 1 0
Sudan 1 0
New Caledonia 1 0
Morocco 1 0
South Korea 1 0
Montenegro 1 0
Georgia 1 0
Guadeloupe 1 0
Martinique 1 0
Panama 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 29068 number of confirmed cases, 217 reported travel history. For 121 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.96 days (median 2 days) and varied by country (n = 950 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 330, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 5% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext