Monkeypox 2022 global epidemiology; Report 2022-08-04

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 99 countries (either confirmed or suspected cases), with 90 confirming transmission, 8 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 25713 confirmed and 1685 suspected cases (as of 2022-08-04; Figure 1A). Since 2022-08-02, 1008 new confirmed cases have been reported, and 2 new countries have been added to the list (Guatemala, Lithuania) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 6308 36
Spain 4577 22
Germany 2781 9
England 2551 9
France 2239 22
Brazil 1475 50
Netherlands 927 5
Canada 822 10
Portugal 633 7
Italy 505 18
Belgium 482 22
Peru 324 29
Switzerland 304 15
Israel 157 18
Austria 135 36
Nigeria 133 0
Democratic Republic Of The Congo 107 0
Denmark 105 38
Sweden 102 20
Ireland 97 14
Mexico 91 51
Chile 68 51
Scotland 65 10
Poland 63 18
Norway 61 19
Australia 45 2
Hungary 42 13
Slovenia 35 6
Ghana 35 2
Greece 33 13
Wales 32 6
Luxembourg 30 57
Czech Republic 25 56
Northern Ireland 24 33
Argentina 23 15
Romania 22 10
Puerto Rico 21 61
Finland 20 17
Colombia 20 66
Malta 17 0
United Arab Emirates 16 0
Singapore 13 18
Croatia 12 20
Serbia 10 0
Iceland 10 11
India 8 100
Estonia 8 60
Central African Republic 8 0
Ecuador 6 100
Cameroon 6 0
Slovakia 6 100
Gibraltar 5 0
Bulgaria 4 0
Saudi Arabia 4 33
Lebanon 4 0
South Africa 3 0
Andorra 3 0
Dominican Republic 3 0
Benin 3 0
Costa Rica 3 0
New Zealand 3 50
Latvia 3 0
Jamaica 2 0
Thailand 2 0
Taiwan 2 0
China 2 0
Japan 2 0
Republic of Congo 2 0
Qatar 2 0
Guadeloupe 1 0
Georgia 1 0
Martinique 1 0
Russia 1 0
South Korea 1 0
Morocco 1 0
Bosnia And Herzegovina 1 0
Bermuda 1 0
Turkey 1 0
New Caledonia 1 0
Barbados 1 0
Venezuela 1 0
Panama 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 25713 number of confirmed cases, 208 reported travel history. For 112 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.99 days (median 2 days) and varied by country (n = 932 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 471, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 5% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext