Monkeypox 2022 global epidemiology; Report 2022-07-28

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 89 countries (either confirmed or suspected cases), with 77 confirming transmission, 9 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 12 have only discarded cases. Overall there are 18921 confirmed and 1654 suspected cases (as of 2022-07-28; Figure 1A). Since 2022-07-26, 34 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
Spain 3738 19
United States 3480 50
Germany 2410 9
England 2325 13
France 1562 7
Netherlands 818 24
Brazil 813 81
Canada 681 12
Portugal 588 14
Italy 426 13
Belgium 311 0
Switzerland 238 10
Peru 208 65
Israel 121 18
Democratic Republic Of The Congo 107 0
Nigeria 101 0
Austria 99 19
Sweden 77 0
Denmark 71 47
Ireland 69 0
Mexico 60 50
Scotland 59 15
Norway 50 8
Chile 45 73
Australia 44 7
Poland 40 42
Hungary 33 10
Wales 30 30
Slovenia 27 0
Greece 20 0
Romania 20 5
Northern Ireland 18 38
Argentina 18 38
Ghana 18 0
Malta 17 88
United Arab Emirates 16 23
Czech Republic 14 16
Luxembourg 14 75
Puerto Rico 13 62
Finland 13 0
Singapore 10 66
Colombia 10 0
Central African Republic 8 0
Croatia 7 16
Cameroon 6 0
Iceland 6 0
Serbia 5 400
Gibraltar 5 0
Estonia 4 0
Slovakia 3 200
South Africa 3 0
Bulgaria 3 0
Benin 3 0
Saudi Arabia 3 200
Latvia 3 50
Dominican Republic 3 0
Republic of Congo 2 0
New Zealand 2 0
Jamaica 2 100
Taiwan 2 0
India 2 0
Ecuador 2 0
Morocco 1 0
Georgia 1 0
Russia 1 0
Martinique 1 0
Bosnia And Herzegovina 1 0
Lebanon 1 0
Panama 1 0
Turkey 1 0
Costa Rica 1 0
Barbados 1 0
Venezuela 1 0
South Korea 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 18921 number of confirmed cases, 191 reported travel history. For 99 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.37 days (median 2 days) and varied by country (n = 900 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 437, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 6% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext