Monkeypox 2022 global epidemiology; Report 2022-07-26

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 89 countries (either confirmed or suspected cases), with 77 confirming transmission, 9 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 12 have only discarded cases. Overall there are 17059 confirmed and 1654 suspected cases (as of 2022-07-26; Figure 1A). Since 2022-07-22, 1325 new confirmed cases have been reported, and 3 new countries have been added to the list (Bermuda, Japan, Qatar) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
Spain 3125 10
United States 2883 46
Germany 2352 15
England 2115 18
France 1562 72
Netherlands 712 8
Brazil 696 98
Canada 681 26
Portugal 588 14
Italy 407 8
Belgium 311 38
Switzerland 234 12
Peru 143 55
Israel 114 18
Democratic Republic Of The Congo 107 0
Nigeria 101 62
Austria 99 19
Sweden 77 32
Ireland 69 27
Denmark 59 59
Scotland 54 17
Mexico 48 77
Norway 46 15
Australia 41 24
Poland 40 81
Chile 39 95
Hungary 32 33
Slovenia 27 3
Wales 24 20
Greece 20 53
Romania 20 25
Ghana 18 0
Malta 17 88
United Arab Emirates 16 23
Northern Ireland 15 25
Luxembourg 14 133
Czech Republic 14 16
Argentina 13 8
Finland 13 0
Colombia 10 42
Puerto Rico 8 0
Central African Republic 8 0
Singapore 8 33
Croatia 7 133
Cameroon 6 100
Iceland 6 0
Gibraltar 5 400
Serbia 5 400
Estonia 4 300
South Africa 3 0
Slovakia 3 200
Latvia 3 50
Bulgaria 3 0
Benin 3 0
Dominican Republic 3 200
Republic of Congo 2 0
Ecuador 2 100
Jamaica 2 100
Taiwan 2 0
New Zealand 2 0
India 2 0
Turkey 1 0
Barbados 1 0
Venezuela 1 0
Bosnia And Herzegovina 1 0
Lebanon 1 0
South Korea 1 0
Saudi Arabia 1 0
Panama 1 0
Georgia 1 0
Morocco 1 0
Martinique 1 0
Russia 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 17059 number of confirmed cases, 187 reported travel history. For 98 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.37 days (median 2 days) and varied by country (n = 900 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 427, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 7% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext