Monkeypox 2022 global epidemiology; Report 2022-07-25

From the Global.health team (info@global.health) • Permalink

Summary

Reporting now includes all cases, including from endemic countries. Choropleth and case count graph are now interactive. Genomic data is filtered using clade membership instead of filtering by genomes after May 2022.

The Monkeypox 2022 outbreak has to date been detected in 86 countries (either confirmed or suspected cases), with 74 confirming transmission, 9 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 12 have only discarded cases. Overall there are 15734 confirmed and 1654 suspected cases (as of 2022-07-25; Figure 1A). Since 2022-07-21, 217 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
Spain 3125 10
United States 2316 27
Germany 2191 13
England 2050 15
France 1448 59
Netherlands 712 8
Brazil 607 95
Canada 604 12
Portugal 515 0
Italy 374 10
Belgium 311 38
Switzerland 216 3
Peru 126 36
Democratic Republic Of The Congo 107 0
Israel 105 9
Nigeria 101 62
Austria 83 0
Sweden 77 32
Ireland 69 27
Scotland 51 10
Denmark 48 29
Norway 46 15
Australia 41 24
Mexico 40 48
Hungary 30 25
Poland 28 27
Slovenia 27 3
Chile 26 30
Wales 23 15
Greece 20 53
Romania 19 18
Ghana 18 0
Northern Ireland 13 8
United Arab Emirates 13 0
Argentina 13 8
Finland 13 0
Czech Republic 12 0
Colombia 10 42
Malta 9 0
Puerto Rico 8 0
Luxembourg 8 33
Central African Republic 8 0
Singapore 6 0
Croatia 6 100
Iceland 6 0
Cameroon 6 100
Gibraltar 5 400
Estonia 4 300
South Africa 3 0
Bulgaria 3 0
Dominican Republic 3 200
Benin 3 0
India 2 0
Taiwan 2 0
Latvia 2 0
New Zealand 2 0
Republic of Congo 2 0
Ecuador 2 100
Morocco 1 0
Venezuela 1 0
Barbados 1 0
Lebanon 1 0
Turkey 1 0
Martinique 1 0
Bosnia And Herzegovina 1 0
Russia 1 0
Saudi Arabia 1 0
South Korea 1 0
Georgia 1 0
Panama 1 0
Slovakia 1 0
Serbia 1 0
Jamaica 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 15734 number of confirmed cases, 179 reported travel history. For 97 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.38 days (median 2 days) and varied by country (n = 893 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 417, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 42.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 8% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext