Monkeypox 2022 global epidemiology; Report 2022-07-19

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 78 countries (either confirmed or suspected cases), with 68 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 13 have only discarded cases. Overall there are 12917 confirmed and 33 suspected cases (as of 2022-07-19; Figure 1A). Since 2022-07-15, 656 new confirmed cases have been reported, and 2 new countries have been added to the list (Barbados, Martinique) (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
Spain 2835 15
Germany 1924 17
United States 1813 109
England 1778 7
France 908 25
Netherlands 656 30
Canada 539 24
Portugal 515 8
Italy 339 16
Brazil 310 40
Belgium 224 0
Switzerland 208 26
Israel 96 31
Peru 92 411
Austria 83 33
Sweden 58 34
Ireland 54 22
Scotland 46 4
Norway 40 29
Denmark 37 27
Australia 33 37
Mexico 27 0
Slovenia 26 44
Hungary 24 0
Poland 22 83
Wales 20 5
Chile 20 53
Ghana 18 0
Romania 16 14
Greece 13 18
Finland 13 0
United Arab Emirates 13 0
Northern Ireland 12 0
Argentina 12 33
Czech Republic 12 50
Malta 9 125
Puerto Rico 8 300
Colombia 7 40
Iceland 6 0
Singapore 6 50
Luxembourg 6 100
South Africa 3 0
Benin 3 0
Bulgaria 3 0
Croatia 3 200
Latvia 2 0
Taiwan 2 100
New Zealand 2 100
South Korea 1 0
Venezuela 1 0
Turkey 1 0
Panama 1 0
Jamaica 1 0
Dominican Republic 1 0
Slovakia 1 0
Morocco 1 0
Serbia 1 0
Ecuador 1 0
Estonia 1 0
Georgia 1 0
Gibraltar 1 0
Lebanon 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 12917 number of confirmed cases, 177 reported travel history. For 96 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.47 days (median 2 days) and varied by country (n = 784 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 374, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 9% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext