Monkeypox 2022 global epidemiology; Report 2022-07-08

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 71 countries (either confirmed or suspected cases), with 61 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 14 have only discarded cases. Overall there are 7492 confirmed and 42 suspected cases (as of 2022-07-08; Figure 1A). Since 2022-07-06, 322 new confirmed cases have been reported, and 2 new countries have been added to the list (Jamaica, Slovakia) (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
Germany 1385 31
England 1285 8
Spain 1258 5
United States 604 52
France 577 15
Portugal 433 7
Netherlands 402 56
Canada 370 28
Italy 233 21
Belgium 168 43
Brazil 142 283
Switzerland 135 62
Israel 59 40
Ireland 44 12
Scotland 40 17
Austria 37 0
Sweden 28 0
Norway 25 47
Hungary 19 0
Ghana 18 0
Denmark 18 0
Australia 17 41
Peru 15 400
Wales 15 50
Slovenia 14 55
Chile 13 116
United Arab Emirates 13 0
Poland 12 0
Romania 11 0
Greece 11 266
Northern Ireland 11 83
Mexico 11 0
Finland 10 150
Czech Republic 8 0
Argentina 6 0
Colombia 5 66
Iceland 4 0
Malta 4 0
Luxembourg 3 0
Benin 3 0
Bulgaria 3 0
South Africa 2 0
Latvia 2 0
Singapore 2 100
Croatia 1 0
Venezuela 1 0
Turkey 1 0
Taiwan 1 0
Morocco 1 0
Estonia 1 0
South Korea 1 0
Georgia 1 0
Serbia 1 0
Gibraltar 1 0
Puerto Rico 1 0
Lebanon 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 7492 number of confirmed cases, 138 reported travel history. For 78 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.73 days (median 2 days) and varied by country (n = 694 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 291, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 40.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 12% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 95% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext