Monkeypox 2022 global epidemiology; Report 2022-07-06

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 66 countries (either confirmed or suspected cases), with 56 confirming transmission, 7 countries continuing to have suspected cases only, and 30 countries having discarded cases that were suspected, out of which 16 have only discarded cases. Overall there are 6947 confirmed and 42 suspected cases (as of 2022-07-06; Figure 1A). Since 2022-07-04, 769 new confirmed cases have been reported (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
England 1285 47
Spain 1258 57
Germany 1242 42
France 577 31
United States 460 50
Portugal 415 6
Netherlands 352 36
Canada 300 8
Italy 233 46
Belgium 168 43
Switzerland 121 49
Brazil 79 295
Israel 52 36
Scotland 40 53
Ireland 39 39
Austria 37 85
Sweden 28 115
Norway 22 29
Hungary 19 58
Denmark 18 0
Ghana 18 0
Peru 15 400
Wales 15 87
United Arab Emirates 13 0
Australia 12 -7
Poland 12 0
Romania 11 0
Mexico 11 0
Northern Ireland 11 266
Finland 10 150
Chile 9 50
Slovenia 9 12
Czech Republic 8 33
Argentina 6 50
Colombia 5 66
Malta 4 0
Iceland 4 33
Luxembourg 3 0
Benin 3 0
Greece 3 0
Bulgaria 3 0
South Africa 2 0
Latvia 2 0
Gibraltar 1 0
South Korea 1 0
Georgia 1 0
Croatia 1 0
Singapore 1 0
Taiwan 1 0
Serbia 1 0
Lebanon 1 0
Venezuela 1 0
Morocco 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 6947 number of confirmed cases, 128 reported travel history. For 73 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.73 days (median 2 days) and varied by country (n = 692 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 289, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 40.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 13% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext