Monkeypox 2022 global epidemiology; Report 2022-07-05

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 67 countries (either confirmed or suspected cases), with 56 confirming transmission, 8 countries continuing to have suspected cases only, and 29 countries having discarded cases that were suspected, out of which 15 have only discarded cases. Overall there are 6178 confirmed and 51 suspected cases (as of 2022-07-05; Figure 1A). Since 2022-07-01, 72 new confirmed cases have been reported (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
Spain 1196 62
England 1185 35
Germany 1054 37
France 498 50
United States 459 88
Portugal 402 10
Canada 287 22
Netherlands 257 0
Italy 192 51
Belgium 117 51
Switzerland 91 33
Israel 42 90
Ireland 39 39
Brazil 37 85
Austria 37 85
Scotland 34 30
Sweden 28 115
Hungary 19 58
Ghana 18 0
Denmark 18 12
Norway 17 325
United Arab Emirates 13 0
Poland 12 0
Australia 12 -7
Romania 11 120
Mexico 11 22
Wales 10 25
Slovenia 9 12
Czech Republic 8 33
Northern Ireland 6 100
Argentina 6 50
Chile 6 100
Iceland 4 33
Malta 4 0
Finland 4 0
Colombia 3 0
Luxembourg 3 0
Peru 3 200
Greece 3 0
Bulgaria 3 0
Latvia 2 0
South Africa 2 100
Morocco 1 0
Venezuela 1 0
Taiwan 1 0
Georgia 1 0
Croatia 1 0
South Korea 1 0
Singapore 1 0
Serbia 1 0
Gibraltar 1 0
Lebanon 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 6178 number of confirmed cases, 126 reported travel history. For 73 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.96 days (median 3 days) and varied by country (n = 623 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 289, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 40.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 14% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext