Monkeypox 2022 global epidemiology; Report 2022-07-01

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 67 countries (either confirmed or suspected cases), with 56 confirming transmission, 8 countries continuing to have suspected cases only, and 29 countries having discarded cases that were suspected, out of which 15 have only discarded cases. Overall there are 5253 confirmed and 56 suspected cases (as of 2022-07-01; Figure 1A). Since 2022-06-29, 331 new confirmed cases have been reported, and 3 new countries have been added to the list (Estonia, Puerto Rico, Turkey) (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
England 1035 18
Germany 969 43
Spain 800 8
France 440 33
Portugal 402 15
United States 351 102
Canada 276 17
Netherlands 257 21
Italy 159 25
Belgium 117 51
Switzerland 81 47
Israel 38 137
Ireland 28 0
Scotland 27 3
Brazil 21 90
Austria 20 0
Hungary 19 58
Denmark 18 38
Ghana 18 0
Norway 17 325
Australia 14 7
United Arab Emirates 13 0
Sweden 13 0
Poland 12 0
Romania 11 120
Mexico 11 22
Wales 9 12
Slovenia 9 12
Czech Republic 6 0
Chile 6 100
Northern Ireland 5 66
Argentina 5 25
Malta 4 0
Finland 4 0
Luxembourg 3 200
Bulgaria 3 50
Iceland 3 0
Greece 3 50
Colombia 3 0
South Africa 2 100
Latvia 2 0
Gibraltar 1 0
South Korea 1 0
Georgia 1 0
Singapore 1 0
Croatia 1 0
Taiwan 1 0
Serbia 1 0
Lebanon 1 0
Venezuela 1 0
Morocco 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 5253 number of confirmed cases, 120 reported travel history. For 71 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.96 days (median 3 days) and varied by country (n = 624 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 289, where we consider a genomic sequence to be related to the current outbreak if it was reported from May 2022 onwards. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 40.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 16% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext