Monkeypox 2022 global epidemiology; Report 2022-06-30

From the Global.health team (info@global.health) • Permalink

Summary

Prior to this report, number of travel history cases and percentage male calculation incorrectly used all cases, instead of only confirmed. Archived reports will be updated soon.

The Monkeypox 2022 outbreak has to date been detected in 66 countries (either confirmed or suspected cases), with 53 confirming transmission, 10 countries continuing to have suspected cases only, and 27 countries having discarded cases that were suspected, out of which 14 have only discarded cases. Overall there are 4922 confirmed and 44 suspected cases (as of 2022-06-30; Figure 1A). Since 2022-06-28, 544 new confirmed cases have been reported, and 1 new country has been added to the list (Benin) (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
Germany 874 47
England 873 13
Spain 800 53
France 440 33
Portugal 391 23
United States 306 96
Canada 276 23
Netherlands 257 53
Italy 159 87
Belgium 117 51
Switzerland 81 76
Israel 38 192
Ireland 28 0
Scotland 26 44
Brazil 20 81
Austria 20 66
Denmark 18 38
Ghana 18 260
Norway 17 750
Australia 13 0
United Arab Emirates 13 0
Sweden 13 30
Poland 12 0
Hungary 12 100
Romania 11 120
Mexico 11 22
Slovenia 8 0
Wales 8 33
Czech Republic 6 0
Chile 6 100
Argentina 4 -20
Malta 4 100
Finland 4 0
Northern Ireland 3 0
Luxembourg 3 200
Iceland 3 0
Greece 3 50
Latvia 2 0
South Africa 2 100
Morocco 1 0
Serbia 1 0
Singapore 1 0
South Korea 1 0
Gibraltar 1 0
Georgia 1 0
Venezuela 1 0
Lebanon 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 4922 number of confirmed cases, 116 reported travel history. For 69 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 4.06 days (median 3 days) and varied by country (n = 603 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 237. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 99 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 40.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 17% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext