Monkeypox 2022 global epidemiology; Report 2022-06-22

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 58 countries (either confirmed or suspected cases), with 45 confirming transmission, 10 countries continuing to have suspected cases only, and 24 countries having discarded cases that were suspected. Overall there are 3126 confirmed and 120 suspected cases (as of 2022-06-22; Figure 1A). Since 2022-06-20, 449 new confirmed cases have been reported, and 2 new countries have been added to the list (Singapore, South Korea) (Figure 1B).

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graph: Travel history and confirmed cases
Figure 1: A) Number of confirmed cases since May 7 2022 per country. Lines show reported travel history between countries and colour indicates the date of travel. B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases. Link to figure
Country Confirmed % difference in cases compared to last week
England 766 69
Spain 520 66
Germany 469 105
Portugal 304 31
France 277 204
Canada 210 32
United States 113 73
Netherlands 95 18
Italy 71 86
Belgium 62 158
Switzerland 41 105
Scotland 18 50
Ireland 14 55
Australia 13 62
United Arab Emirates 13 0
Poland 12 1100
Denmark 12 200
Israel 11 175
Austria 11 266
Sweden 10 66
Mexico 9 350
Brazil 8 166
Slovenia 7 0
Hungary 6 500
Czech Republic 6 0
Wales 6 50
Romania 5 400
Argentina 5 66
Ghana 5 0
Northern Ireland 3 50
Finland 3 0
Norway 2 0
Malta 2 100
Greece 2 100
Latvia 2 0
Morocco 1 0
Gibraltar 1 0
Venezuela 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 3126 number of confirmed cases, 124 reported travel history. For 80 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 3.37 days (median 3 days) and varied by country (n = 384 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 163. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 22% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 96% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext