Monkeypox 2022 global epidemiology; Report 2022-09-21

From the Global.health team (info@global.health) • Permalink

Summary

The Monkeypox 2022 outbreak has to date been detected in 118 countries (either confirmed or suspected cases), with 112 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 63780 confirmed and 3673 suspected cases (as of 2022-09-21; Figure 1A). Since 2022-09-19, 1373 new confirmed cases have been reported, and 1 new country has been added to the list (Bahrain) (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 23731 5
Spain 7083 1
Brazil 7019 12
France 3889 1
Germany 3570 0
England 3412 0
Peru 2091 5
Colombia 1653 31
Mexico 1367 30
Canada 1362 0
Netherlands 1209 1
Portugal 908 1
Italy 837 2
Belgium 744 0
Chile 728 26
Switzerland 502 2
Austria 301 3
Nigeria 277 25
Argentina 265 19
Israel 250 1
Democratic Republic Of The Congo 195 0
Denmark 183 0
Sweden 179 1
Ireland 173 0
Poland 167 4
Puerto Rico 163 7
Bolivia 149 19
Australia 132 2
Scotland 93 1
Norway 89 4
Ghana 84 0
Hungary 75 0
Greece 69 2
Ecuador 68 0
Czech Republic 65 4
Luxembourg 55 0
Slovenia 46 0
Wales 46 0
Romania 38 2
Northern Ireland 34 9
Finland 33 0
Malta 33 0
Dominican Republic 31 106
Serbia 31 0
Croatia 27 0
Singapore 19 18
United Arab Emirates 16 0
Slovakia 14 0
Panama 13 8
Jamaica 13 8
Guatemala 13 8
India 12 9
Iceland 12 0
Turkey 11 0
Lebanon 11 0
Estonia 11 0
Thailand 8 14
Saudi Arabia 8 0
Central African Republic 8 0
Cameroon 7 0
Martinique 7 0
Bulgaria 6 0
Sudan 6 50
Gibraltar 6 0
Lithuania 5 0
Latvia 5 25
Uruguay 5 0
South Africa 5 0
Cyprus 5 0
Venezuela 5 66
New Zealand 5 0
Costa Rica 4 33
Qatar 4 33
Philippines 4 0
El Salvador 4 100
Andorra 4 0
Japan 4 0
Honduras 4 0
Benin 3 0
Aruba 3 0
Morocco 3 0
Taiwan 3 -25
Republic of Congo 3 0
Bosnia And Herzegovina 3 0
Monaco 3 0
Guyana 2 0
South Sudan 2 0
South Korea 2 0
Liberia 2 0
Georgia 2 0
Moldova 2 0
Greenland 2 0
Russia 2 0
Cuba 2 0
Montenegro 2 0
Bahamas 2 0
Barbados 1 0
Iran 1 0
Bermuda 1 0
Saint Martin (French part) 1 0
Curaçao 1 0
Indonesia 1 0
Paraguay 1 0
New Caledonia 1 0
Guadeloupe 1 0
Jordan 1 0
Hong Kong 1 0
Egypt 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 63780 number of confirmed cases, 248 reported travel history. For 140 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.41 days (median 2 days) and varied by country (n = 1059 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 797, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is United Kingdom. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext