Monkeypox 2022 global epidemiology; Report 2022-09-23

From the Global.health team (info@global.health) • Permalink

Summary

This is the final briefing report as we have discontinued line-list reporting as of 2022-09-22. Our team completed a 100 days mission to provide early situational awareness through open-access, global line-list data for the 2022 monkeypox outbreak. Check-out our newsletter to see what's happening next with our data.

The Monkeypox 2022 outbreak has to date been detected in 118 countries (either confirmed or suspected cases), with 112 confirming transmission, 6 countries continuing to have suspected cases only, and 33 countries having discarded cases that were suspected, out of which 11 have only discarded cases. Overall there are 64851 confirmed and 3673 suspected cases (as of 2022-09-23; Figure 1A). Since 2022-09-21, 617 new confirmed cases have been reported (Figure 1B).

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Figure 1: A) Number of confirmed cases per country. Lines show reported travel history between countries.
B) Number of cumulative confirmed cases and number of countries who have reported confirmed cases.
Country Confirmed % difference in cases compared to last week
United States 24198 5
Brazil 7205 8
Spain 7083 0
France 3934 1
Germany 3590 0
England 3412 0
Peru 2251 9
Colombia 1653 31
Canada 1388 1
Mexico 1367 30
Netherlands 1221 0
Portugal 908 0
Italy 837 1
Chile 783 14
Belgium 757 1
Switzerland 503 1
Austria 304 2
Nigeria 277 0
Argentina 265 19
Israel 250 1
Democratic Republic Of The Congo 195 0
Sweden 186 3
Denmark 183 0
Ireland 178 2
Poland 173 8
Puerto Rico 170 4
Bolivia 155 15
Australia 132 0
Ecuador 93 36
Scotland 93 1
Norway 90 1
Ghana 84 0
Hungary 77 2
Greece 72 4
Czech Republic 66 6
Luxembourg 55 0
Slovenia 46 0
Wales 46 0
Serbia 40 29
Romania 39 5
Northern Ireland 34 9
Finland 33 0
Malta 33 0
Dominican Republic 31 3
Croatia 29 7
Singapore 19 0
United Arab Emirates 16 0
Guatemala 15 25
Slovakia 14 0
Panama 13 8
Jamaica 13 8
Iceland 12 0
India 12 0
Lebanon 11 0
Estonia 11 0
Turkey 11 0
Central African Republic 8 0
Saudi Arabia 8 0
Thailand 8 14
Cameroon 7 0
Martinique 7 0
Bulgaria 6 0
Uruguay 6 20
Gibraltar 6 0
Sudan 6 50
Honduras 6 50
Lithuania 5 0
Cyprus 5 0
Qatar 5 25
Venezuela 5 66
South Africa 5 0
New Zealand 5 0
Latvia 5 25
Philippines 4 0
Costa Rica 4 0
Andorra 4 0
El Salvador 4 100
Japan 4 0
Curaçao 3 200
Morocco 3 0
Aruba 3 0
Monaco 3 0
Republic of Congo 3 0
Taiwan 3 0
Benin 3 0
Bosnia And Herzegovina 3 0
South Korea 2 0
Greenland 2 0
Guyana 2 0
Bahamas 2 0
South Sudan 2 0
Georgia 2 0
Russia 2 0
Liberia 2 0
Montenegro 2 0
Moldova 2 0
Cuba 2 0
Saint Martin (French part) 1 0
Indonesia 1 0
Barbados 1 0
Bermuda 1 0
Jordan 1 0
Hong Kong 1 0
Egypt 1 0
Guam 1 0
Iran 1 0
Guadeloupe 1 0
New Caledonia 1 0
Paraguay 1 0

Table 1: Number of confirmed cases by country (highest to lowest) and percentage change since last week.

Of the 64851 number of confirmed cases, 248 reported travel history. For 140 cases, travel history location was unknown.

The mean delay between confirmation and entry of suspected case was 5.42 days (median 3 days) and varied by country (n = 1066 total number of cases where the dates of suspected and confirmed was known; Figure 2). Most countries do not report suspected cases.

graph: Delay to confirmation by country
Figure 2: Delay to confirmation by country. Link to figure

Genomic data is being reported via multiple open source repositories. In order to support ongoing genomic surveillance and improve representativeness of genomic sequences we here plot the relationship between number of genomic sequences vs. number of confirmed cases (Figure 3). The (combined) number of genomic sequences of the current outbreak is 846, where we consider a genomic sequence to be related to the current outbreak if it was reported in 2022 with Clade IIb. The country with the highest number of genomic sequences reported is Germany. A comparison between the number of genomes and number of confirmed cases is below (Figure 3).

graph: Number of sequences from Nextstrain and confirmed cases
Figure 3: Number of sequences (downloaded via Nextstrain) and confirmed cases. Link to figure

The age and gender ratio is shown in Figure 4. 98 percent of cases (for which there was an entry for gender) are described as male. The mean age of confirmed cases is 41.

graph: Age and gender distribution
Figure 4: Age and gender distribution of monkeypox confirmed cases in 2022. 3% of confirmed cases include sufficient metadata to be included in this figure. Of these cases, 94% include reported age ranges that span multiple age categories. Under such circumstances, counts are evenly distributed among the categories that capture the reported age range. Link to figure

Data accessibility and reproducibility: All data used in this report are available from: https://github.com/globaldothealth/monkeypox. Should you identify any issues or have questions please raise an issue on GitHub or write to us: info@global.health. Latest data can be downloaded from here: https://github.com/globaldothealth/monkeypox/blob/main/latest.csv

Please see a description of the data curation process here: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00359-0/fulltext